IAD | Breaking The Mould

Inhalational Alzheimer’s disease: an unrecognized — and treatable — epidemic

Type 3 Alzheimer's disease is the result of exposure to toxins and is most commonly inhalation alzheimer's disease (IAD), a manifestation of Chronic Inflammatory Response Syndrome (CIRS) due to biotoxins such as mycotoxins
Type 3 AD is unique to types 1 and 2 for two reasons. The onset is typically younger (40s - 60s), the family history is typically negative (or only positive at a much later age), symptom onset usually follows a period of great stress, sleep loss, anesthesia, menopause/ andropause, and it does not present like amnesia (i.e. loss of memory) but is instead 'cortical' (executive dysfunction, confusion, problems completing basic tasks), and is often preceded by or accompanied with depression
Alongside these symptoms, imaging studies show extra-hippocampal disease, more general cerebral atrophy and frontal-temporal-parietal abnormalities
All 6 of the type 3 Alzheimers disease patients in this study had a significant history of an exposure to mycotoxins and majority meet the criteria for CIRS

Patient 1

52 year old woman, a two year history of cognitive decline beginning with dyscalculia
Hey cognitive decline was preceded by severe stress, employment changes, menopause at 51, and four episodes of general anethesia for relatively minor procedures
Family history was negative for dementia and her symptoms weren't to do with amnesia but more cortical (i.e. cognitive capability)
MRI showed global cereberal and cerebellar atrophy (where parts of the brain shrink in size)
The presence of amyloid plaques (a key feature of alzheimer's disease) was positive in scans
Other tests strongly supported the case for Alzheimer's disease
She had moved into a new home 2 years before the onset of symptoms and symptoms worsened when returning from travel
Evaluation of the home showed Stachobotrys, Penicillium, Asperlligus (All types of myctoxin producing moulds)
Her nasal cavity was positive for MARCoNS (a Bacteria and fungal culture found in chronic mould illness cases and CIRS)
These factors together were strongly suggestive of a diagnosis of CIRS
After just 5 weeks of the Shoemaker protocol (to treat mould toxicity) she began to show modest improvement
Conclusion : The patient fulfilled criteria for both Alzheimer's disease and CIRS. Her symptoms were typical of Type 3 and not Type 1 & 2 (due to the lack of amnesia and predominantly cognitive decline). Her family was negative for Azheimer's (i.e. it was not geneticlally hereditary), she had been exposed to mycotoxins in the home which show neurotoxic effects and her test values were strongly supportive of CIRS.

Patient 2

A 59 year old man had word finding difficulties, and difficulties with arithmetic which was preceded by depression for seven years.
He was reported to have been a 'type A' personality with a 'high powered position' whose neurological symptoms had begun after 2 years of the most stressful time in his career
His personality changed and he became passive and timid
Neuropsychological testing showed profound impairment to speak fluently, executive functioning, attention, overall mental status, processing and visual memory
A diagnosis of Alzheimer's disease was made at a nationally recognised Alzheimer's disease clinic
Due to the profile of Type 3 AD, his background was investigated. He had spent time in foreclosed homes that had suffered water damage
Genetic testing was strongly associated with hypersensitivity to biotoxins
His naval cavity was colonised with MARCoNS (a common symptom associated with CIRS)
He was treated for a mould toxicity protocol and improvement in cognition showed after several weeks
Evaluation : The patient was typical for Type 3 AD and presentation of CIRS. His relatively rapid response to treatment with the Shoemaker protocol supports the diagnosis of CIRS and relationship to Type 3